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Generative Now | AI Builders on Creating the Future

Lightspeed Venture Partners
Generative Now | AI Builders on Creating the Future
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  • Bucky Moore: The Next Decade of AI Infrastructure
    This week, Lightspeed Partner Mike Mignano sits down with his colleague Bucky Moore, a fellow partner at Lightspeed to explore the rapidly shifting landscape of AI and infrastructure. They unpack the evolution from hardware to cloud to AI-native architectures, the growing momentum behind open-source models, and the rise of AI agents and reinforcement learning environments. Bucky also shares how his early days at Cisco shaped his bottom-up view of enterprise software, and why embracing the new is the key to spotting trillion-dollar opportunities.Episode Chapters: (00:00) Introduction to the Conversation(00:38) Bucky Moore's Background and Early Career(01:39) Insights from Cisco: Old World Meets New World(03:54) Transition to Venture Capital(08:15) The Evolution of Infrastructure Investment(15:50) Impact of AI on Infrastructure(24:37) Training AI Agents: Challenges and Innovations(25:07) The Future of Reinforcement Learning Environments(25:51) Infrastructure for AI Agents(26:49) Emerging Opportunities in AI Infrastructure(28:58) The Impact of Salesforce's Data Policies(33:00) The Evolution of AI Compute(39:47) The Role of New AI Architectures(42:47) The Future of Venture Capital in AI(46:44) Predicting the Next Trillion-Dollar AI CompaniesStay in touch:www.lsvp.comX: https://twitter.com/lightspeedvpLinkedIn: https://www.linkedin.com/company/lightspeed-venture-partners/Instagram: https://www.instagram.com/lightspeedventurepartners/Subscribe on your favorite podcast app: generativenow.coEmail: [email protected] content here does not constitute tax, legal, business or investment advice or an offer to provide such advice, should not be construed as advocating the purchase or sale of any security or investment or a recommendation of any company, and is not an offer, or solicitation of an offer, for the purchase or sale of any security or investment product. For more details please see lsvp.com/legal.
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  • Moritz Baier-Lentz: How AI Is Rewriting the Rules of Gaming
    This week, Lightspeed Partner Mike Mignano sits down with Moritz Baier-Lentz, Partner and Head of Gaming and Interactive Media at Lightspeed. From the world’s #1 ranked Diablo II player to Goldman Sachs banker to VC, Moritz has lived multiple lives—all shaped by a deep passion for games. In this episode, Moritz joins Michael Mignano to talk about the AI revolution in gaming: how generative tech is transforming studios, gameplay, and player experiences. They dive into what makes games work in 2025 and why the next billion-dollar games may not look like games at all. Episode Chapters: 00:00 Introduction and Guest Overview01:16 Moritz Bayer's Gaming Journey02:53 The Economics of Gaming06:28 Competitive Gaming and Personal Growth09:32 Marathon Adventures and Life Philosophy13:16 Venture Capital in Gaming24:38 AI's Impact on Gaming29:50 Future of Gaming and AI39:40 Game Theory Podcast and Final ThoughtsStay in touch:www.lsvp.comwww.lsvp.com/gametheory X: https://twitter.com/lightspeedvpLinkedIn: https://www.linkedin.com/company/lightspeed-venture-partners/Instagram: https://www.instagram.com/lightspeedventurepartners/Subscribe on your favorite podcast app: generativenow.comEmail: [email protected] content here does not constitute tax, legal, business or investment advice or an offer to provide such advice, should not be construed as advocating the purchase or sale of any security or investment or a recommendation of any company, and is not an offer, or solicitation of an offer, for the purchase or sale of any security or investment product. For more details please see lsvp.com/legal.
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  • How Jobs Will Change as AI Gets Better
    What is the future of AI in the workplace? What kinds of jobs would you trust an AI to do? In this episode of Generative Now, host and Lightspeed Partner Michael Mignano explores how AI is transforming the workforce, with insights from four sharp thinkers: Semil Shah, founding general partner at Haystack and Lightspeed Venture Partners, on the risks of replacing junior talent with agents, Suno Co-founder Mikey Schulman on AI’s power to unlock creativity, Anu Atluru, founder, physician and angel investor, on how AI is reshaping medicine, and Marissa Mayer, former CEO of Yahoo and current CEO of Sunshine, on what companies must do now to adapt—or risk being left behind.Episode Chapters00:00 Introduction: AI and the Future of Work00:20 Exploring AI's Impact on the Workforce01:14 The Co-Pilot Phase of AI02:47 AI in Investment Banking and Consulting06:00 Artificial Super Intelligence: The Next Frontier09:33 Mikey Shulman on AI's Role in Creativity11:59 Anu Atluru on AI Transforming Medicine20:18 Marissa Mayer on AI's Organizational Impact26:56 Conclusion: Embracing AI's PotentialStay in touch:www.lsvp.comX: https://twitter.com/lightspeedvpLinkedIn: https://www.linkedin.com/company/lightspeed-venture-partners/Instagram: https://www.instagram.com/lightspeedventurepartners/Subscribe on your favorite podcast app: generativenow.coEmail: [email protected] content here does not constitute tax, legal, business or investment advice or an offer to provide such advice, should not be construed as advocating the purchase or sale of any security or investment or a recommendation of any company, and is not an offer, or solicitation of an offer, for the purchase or sale of any security or investment product. For more details please see lsvp.com/legal.
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  • Reinventing Wall Street: Rogo’s AI Revolution with Gabriel Stengel
    This week, Lightspeed Partner Mike Mignano sits down with Gabriel Stengel, founder and CEO of Rogo, to explore how AI is transforming the world of finance. Gabe shares his journey from sleepless nights as a junior investment banker at Lazard to building Rogo, a cutting-edge AI platform that automates the grueling work of benchmarking, earnings analysis, and pitch deck creation in seconds. They discuss the origins of Rogo from Gabe’s time at Princeton, the challenges of building AI tools for elite financial institutions, and why the next generation of analysts might just be digital. Gabe also unpacks the technical edge that sets Rogo apart and the ways in which financial services may look very different in the near future. Episode Chapters: (00:00) Introduction to the Interview(00:55) Gabe Stengel's Background and Rogo's Inception(02:44) Early Challenges and Evolution of Rogo(07:29) The Role of AI in Finance(12:07) Investor and Customer Reception(13:49) Pivotal Moments and Product Market Fit(21:53) Balancing Enterprise Security and Feature Development(23:45) Navigating the Challenges of AI Startup Speed(25:45) Rogo's Impact on Investment Banking Workflows(28:34) AI's Role in Professional Services and Legal Work(32:33) Future of Rogo and Financial Services(37:18) Challenges and Strategies in Enterprise Sales(42:02) Conclusion and Final ThoughtsStay in touch:www.lsvp.comX: https://twitter.com/lightspeedvpLinkedIn: https://www.linkedin.com/company/lightspeed-venture-partners/Instagram: https://www.instagram.com/lightspeedventurepartners/Subscribe on your favorite podcast app: generativenow.coEmail: [email protected] content here does not constitute tax, legal, business or investment advice or an offer to provide such advice, should not be construed as advocating the purchase or sale of any security or investment or a recommendation of any company, and is not an offer, or solicitation of an offer, for the purchase or sale of any security or investment product. For more details please see lsvp.com/legal.
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  • Mike Krieger: Product Building Lessons from Instagram and Anthropic (Encore)
    This week, we are revisiting a conversation between Lightspeed partner Michael Mignano and Anthropic’s head of product, Mike Krieger. Mike is known for co-founding Instagram, one of the most beloved pieces of consumer technology, and now he has taken his talents to Anthropic. They discuss the challenges AI product builders face and the evolution of product innovation and draw parallels between two transformative eras: the social media revolution that gave birth to Instagram and today's AI renaissance. Episode Chapters: (00:00) Introduction(00:54) Mike Krieger's Journey to Anthropic(03:17) Building Product Strategy at Anthropic(07:43) Rapid Iteration and Safety(10:58) Differentiating AI Models and User Experience(17:57) Impact of AI on Consumer Products and Business Models(24:39) Enterprise vs. Consumer Product Strategy(29:19) AI in Personal Life Management(30:15) Open Source and Claude Integrations(33:09) AI-Assisted Product Development(37:13) Scaling Teams and Processes at Anthropic(42:17) Reflections on AI and Future ProspectsStay in touch:www.lsvp.comX: https://twitter.com/lightspeedvpLinkedIn: https://www.linkedin.com/company/lightspeed-venture-partners/Instagram: https://www.instagram.com/lightspeedventurepartners/Subscribe on your favorite podcast app: generativenow.coEmail: [email protected] content here does not constitute tax, legal, business or investment advice or an offer to provide such advice, should not be construed as advocating the purchase or sale of any security or investment or a recommendation of any company, and is not an offer, or solicitation of an offer, for the purchase or sale of any security or investment product. For more details please see lsvp.com/legal.
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Om Generative Now | AI Builders on Creating the Future

Generative Now is a weekly series from Lightspeed, highlighting the stories, strategies and insights behind today's most exciting AI companies and how they’ll change everything about the way we work. Inspired by the popular in-person Generative Meetups in places like New York, San Francisco, LA and Europe, host and Lightspeed Partner Michael Mignano will speak with founders, engineers, designers and other leaders that are leveraging AI to take their product to new heights. Listen and follow Generative Now wherever you get your podcasts.
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